The Fugitive (1916)

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Margery Carew and her widowed sister, Anna Prentice, find work in a brokerage firm, James Gray, the junior partner, soon falls in love with Margery, while his boss, William Cleves, does his best to seduce Anna. In fighting off William's advances, Anna kills him, but Margery, hoping to protect Anna's child, takes the blame and then escapes to the West, after which she gets married and begins a new life. Following a lengthy search, the police manage to track her down, but Margery still refuses to save herself by telling the truth about the murder, even though Anna and her child died several years before in a car crash. Finally, however, because he still loves her and because he has been stricken by a deadly disease that will kill him in a few months, James confesses to the murder, thereby freeing Margery to return to her husband.